Post Date December, 03 2023
Many patients feel that traditional Chinese medicine is ineffective in treating nephrotic syndrome, so they want to know what specific drugs Western medicine has for treating nephrotic syndrome. Experts say that Western medicine usually uses some hormonal drugs. Initially, using hormonal drugs has a significant effect, but there may be a significant dependence. Therefore, after using hormonal drugs in large quantities, it is necessary to gradually reduce the dosage or use other drugs.
Nephrotic syndrome is a group of symptoms introduced by various causes, characterized by symptoms such as high proteinuria, hypoproteinemia, edema, and hyperlipidemia. It can be divided into primary nephrotic syndrome and secondary nephrotic syndrome according to its etiology. The commonly used hormones for the treatment of nephrotic syndrome during the reduction phase will be introduced.
During the dosage reduction treatment stage, high-dose hormones are usually used for 8 weeks and the dosage needs to be reduced. The weekly dosage reduction is 10% of the original daily dosage, and in adults, it is generally 5 milligrams per week.
1. If there is no improvement or even deterioration after 8 weeks of high-dose treatment, it is estimated that continued medication will not be effective (hormone ineffective type) after carefully excluding factors that may also affect the efficacy, such as infection. The dosage should be quickly reduced for short-term discontinuation. If possible, it is best to send it to a higher-level hospital for kidney biopsy.
2. If the nephrotic syndrome is partially relieved after treatment, the hormone should be reduced to a small dose and changed to a two day dose, followed by a morning meal the next day.
3. If a large dose of hormone is relieved quickly or within 6 weeks, the original dose can be used to consolidate for 2 weeks after the remission, and then the dosage can be reduced.
If it is a minor variant of kidney disease, 90% of pediatric patients complete remission after 4 weeks, so it is usually taken for 4 weeks, followed by another 2 weeks to enter the dosage reduction stage. Adults experience slower remission and usually require the use of hormones for 8 weeks in order to determine whether the hormones are effective for the case of nephrotic syndrome.
When using hormonal drugs for nephrotic syndrome, it is important not to exceed three months. It is not only important to pay attention to the duration of medication, but also to control the dosage of medication, especially during the dosage reduction phase. It is important to choose better drugs for the treatment of nephrotic syndrome.
