Post Date December, 03 2023
What are the diagnostic methods for nephrotic syndrome? Nephrologists from Phoenix Traditional Chinese Medicine point out that the diagnosis of nephrotic syndrome can be divided into two parts: 1. Diagnosis based on the symptoms of nephrotic syndrome; 2. Diagnose through examination of nephrotic syndrome. Let's give a detailed introduction below.
1、 Diagnose by eliminating the symptoms of nephrotic syndrome
1. There is concave edema throughout the body, particularly on the face, lower limbs, and scrotum. There is often ascites, and the overall condition is generally good without hypertension.
2. Urinary insufficiency, urinary protein mostly ranging from+++to++++, with a quantitative value greater than 0.1g/(kg · d). Occasionally, there are a small amount of red blood cells on uroscopy.
3. The total plasma protein is lower than normal, and the decrease in albumin is more significant (<30g/L). Serum protein electrophoresis shows a decrease in albumin ratio, an increase in globulin ratio, and a decrease in r globulin ratio. Blood cholesterol significantly increased (>5.7mmol/L), and serum complement levels were normal.
4. Renal function is generally normal, and when there is significant oliguria during the edema period, there may be temporary mild azotemia.
2、 Diagnosis of nephrotic syndrome through examination
1. Selective proteinuria and determination of C3FDP in urine: Type I is selective proteinuria with C3 and FDP values that are normal. Type II is non-selective proteinuria with C3 and FDP values that often exceed normal.
2. Urinary routine examination: In addition to a large amount of protein in the urine, there may be transparent or granular tubules, and sometimes there may also be adipose tubules. Type II: Centrifuge urine red blood cells<10/HP; Type II>10 units/HP.
3. ESR growth rate: usually 40-80mm/h, and the ESR growth rate is often parallel to edema.
4. Blood biochemical examination: Except for a decrease in total plasma protein, white blood cells can be inverted and blood cholesterol type I and type II may not increase.
5. Renal function examination: Type I is normal, and Type II has varying degrees of abnormalities.
6. Protein electrophoresis: α 2 or β Can significantly increase in height α one γ Globulin is mostly low.
7. Living tissue examination of the kidney: ultrastructural and immunopathology observations can provide histomorphological basis.
The above introduces the diagnostic methods for nephrotic syndrome. For patients and friends, when they experience symptoms related to nephrotic syndrome, they should go to the hospital for examination of nephrotic syndrome, striving for early detection and treatment.
