Six major factors causing hydatidiform mole: three types of women need to pay attention to prevention

The emergence of raisins causes special pain for many women, not only affecting normal pregnancy, but also seriously endangering women's health. It is necessary to pay attention to reasonable prevention.

Raisins are prone to female infections

1. Age: Women under 20 years old or over 40 years old.

2. Past medical history: Women with raisins.

3. Abortion: More than 2 miscarriages.

The reason for raisins

1. Nutritional factors: Raisins are commonly found in gourmet countries and therefore related to nutrition. Studies have found that patients with gestational trophoblastic tumors (GTT) have low serum folate activity, but insufficient folate during embryonic angiogenesis can affect thymus synthesis, leading to embryonic death and insufficient blood vessels in placental villi

2. Infection factors: Many authors believe that raisins are related to viral infection, but no real evidence has been found so far.

3. Endocrine imbalance: The occurrence of raisins is related to inadequate or declining ovarian function, and is therefore more common in women under 20 years old and over 40 years old. Animal experiments have shown that removing the ovaries in early pregnancy can cause blister like changes in the placenta, suggesting that insufficient estrogen may be the cause of hydatidiform mole.

4. Pregnant egg defect: it may be related to the dysplasia of the egg itself.

5. Ethnic factors: the differences in the incidence rate of raisins among different races are of concern. It is reported that the incidence rate of raisins among African American women is only half that of other women. In Singapore, the incidence rate of hydatidiform mole of Eurasian race is twice as high as that of Chinese, Indian and Malaysian.

6. Overexpression of proto-oncogenes and inactivation of tumor suppressor genes: Proto-oncogenes and tumor suppressor genes are genes that control cell growth and differentiation. Activation and overexpression of proto-oncogenes, as well as inactivation of tumor suppressor genes, are related to the occurrence of tumors.

Harm of hydatidiform mole

1. Partial abortion of hydatidiform mole: After natural abortion or suction abortion, there may be residual vesicular fetal masses. Patients with hydatidiform mole who have had a natural abortion for a short period of time before admission and are able to undergo curettage surgery should undergo immediate curettage. For those who have been discharged for a long time or have been infected, antibiotics should be used to control for a few days before undergoing uterine cleaning.

2. Malignant transformation: Malignant transformation into erosive raisin or velvet cancer. The malignant transformation rate is approximately 10-20%.

3. Massive bleeding: If the raisin is not diagnosed and treated in a timely manner, repeated bleeding, uterine bleeding, bleeding, and spontaneous discharge can occur. On the basis of anemia, hemorrhagic shock and even death can occur. Therefore, hydatidiform mole should be treated as an emergency, as short-term delay may cause more blood loss and harm the patient.