Pruritus is one of the four common methods for vulvar leukoplakia. Please tell me the effective judgment

Vulvar leukoplakia is a gynecological disease that we are familiar with, and it is also a serious disease that requires our attention. We should also pay attention to changes in the external genitalia in daily life. If abnormal conditions occur, timely examination is necessary.

Symptoms of vulvar leukoplakia

1. Pruritus: Firstly, the external genitalia is itchy, especially at night, where itching becomes more severe. The degree of itching is related to the time of disease occurrence, menstrual cycle, climate changes, daily diet, living environment, emotional changes, etc. It is usually an intermittent attack that patients cannot tolerate due to itching. After scratching, there will be multiple scratches and redness in the external vagina, and over time, local areas are prone to ulceration, cracking, ulceration, and secondary infections.

2. Excessive keratinization: In the early stage, excessive keratinization is also the focus of analyzing symptoms of vulvar leukoplakia. Limited or diffuse white thickening of the skin mucosa of the external genitalia, such as leather, wrinkles, scales, and eczema. The skin color of the external genitalia is mostly purple red or light red, appearing as gray white or gray blue, mixed with clearly defined white keratinized plaques of different shapes and sizes. The genital area is significantly atrophied, the foreskin of the penis is thick, the keratinization is obvious, the texture of the labia majora is thick, and the pigmentation is reduced.

3. Rough skin: The patient's affected skin is rough, as thick as moss, and is prone to dryness and cracking when scratched. In addition, local pigmentation will decrease, and the labia majora and labia minora will usually turn white. When the condition is mild, the external genitalia undergoes mild atrophy. In severe cases, the penis undergoes atrophy, with adhesions of the labia and labia, partially or completely disappearing. Later, the vaginal opening becomes narrower and the elasticity disappears, affecting normal urination and marital life.

Vulvar leukoplakia examination

1. Local examination: Through careful observation of the cervical region, white spot areas can be found, but lesions with incomplete keratinization cannot be identified with the naked eye.

2. Iodine solution test: The principle of this vulvar leukoplakia test method is that epithelial keratinization and incomplete keratinization lack glycogen storage capacity, and applying iodine without local staining can detect the extent of the lesion. But the iodine test is non-specific, such as cervical erosion, ectropion, and precancerous lesions, which also show positive results.

3. Electronic colposcopy examination: This method of external vaginal leukoplakia examination uses an electronic colposcopy to expand the observation of cervical lesions, which is significantly easier than observing cervical leukoplakia with the naked eye. Based on local diagnosis, iodine test for vulvar vitiligo, and colposcopy examination, it is generally not difficult to diagnose. But more importantly, further examination should be conducted after the discovery of vitiligo to avoid the omission of early cervical cancer coexisting with vitiligo.