Post Date December, 03 2023
There are many theories about the etiology of BPH, which can be described as diverse, such as neobiological theory, arteriosclerosis theory, inflammation theory, endocrine theory, body size, race, social factors, metabolic and nutritional factors, but most of them have not been universally recognized, so the etiology of BPH has not yet been determined. It is also very likely that the cause itself is the result of comprehensive factors. Let's see how the doctors of Kunlun Andrology Hospital introduced them.
1. The reasons related to endocrine disorders are:
(1) Prostatic hyperplasia did not occur in those who had testicles removed before puberty.
(2) The hyperplasia of prostate can degenerate after testicular resection.
(3) Biochemical determination of patients with benign prostatic hyperplasia is often accompanied by abnormal product of androgen dihydrotestosterone
(4) It can be used to stimulate the endocrine to form animal models of prostatic hyperplasia.
Those who hold this view believe that the endocrine function of the prostate is a part of the whole endocrine, or an endocrine effector. The development of the prostate and the maintenance of its physiological state depend on sufficient androgens in the body, especially the balance between androgens and estrogen. It can be seen that the pathogenesis of BPH is related to both androgen and estrogen. Therefore, some people believe that the imbalance of androgen and estrogen in the body may be one of the causes of BPH in the elderly.
2. Aging factors and cell aging related cell aging is one of the basic problems of life science. Cell aging refers to the loss of proliferation of somatic cells, but the cell metabolism is still very active. Cell aging is related to age. With the growth of age, the process of cell aging is accelerated, and the weight of prostate is directly related to cell aging. Cell aging is only seen in the epithelium in pathology, and the accumulation of aging working skin may play an important role in the occurrence of prostatic hyperplasia.
3. New blood vessels form F. 1kman (1998) believed that the occurrence of BPH depends on neovascularization. The proliferation of any entity and the growth and metastasis of tumor require neovascularization. Without new angiogenesis, the growth of proliferative entity and tumor is difficult to exceed a few millimeters. This new concept of proliferative entity and tumor formation has been accepted by everyone.
