About a quarter of the world's population, around 1.7 billion people, suffer from varying degrees of anemia, with iron deficiency anemia being the most common, with 1 billion people. In the treatment of kidney disease, anemia is also a headache for both doctors and patients, and some experienced kidney disease experts often exclaim that kidney disease is not difficult to treat, as long as the anemia is controlled!
What are the hazards of renal anemia?
After anemia, oxygen cannot be delivered to various parts of the body normally, which can affect the whole body. The following three aspects are more important:
1. Renal anemia can cause partial organ hypoxia, increased heart rate, increased cardiac work, left ventricular hypertrophy, exacerbating heart failure and myocardial ischemia;
2. Long term anemia can lead to weakened ovarian or testicular endocrine function;
3. The most serious is that it can cause immune dysfunction, thereby increasing the chances of infection and, in severe cases, endangering life.
Why do kidney disease patients suffer from anemia?
Although iron deficiency is the main cause of anemia overall, in kidney disease, the main cause of anemia is not iron deficiency, but a decrease in erythropoietin caused by kidney damage.
In addition, after kidney damage, a large amount of toxins in the body can reduce the lifespan of red blood cells, leading to anemia; Also, due to insufficient protein intake and excessive loss of urine protein, it can lead to insufficient hemoglobin synthesis. Also... it's quite confusing, as shown in the figure below:
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So how to treat it?
1. Oral administration. Androgens, cobalt chloride, and iron can be taken orally as needed. When anemia occurs, there are often experiences of stomach discomfort and blackening of feces. Taking iron supplements can alleviate stomach discomfort (which also reduces iron absorption). Vitamin D helps the body's ability to absorb iron, so taking oral iron supplements and orange juice is beneficial.
2. Injection. Sometimes oral iron therapy has a slow effect, as the body can only absorb up to 6 milligrams of iron from the gastrointestinal tract every day. At this time, it is necessary to intramuscularly inject norepinephrine and testosterone propionate according to different conditions. In many cases, patients may lose over 1000 milligrams of iron and require several months to supplement. At this time, erythropoietin should be given to increase the rate of red blood cell production to ensure sufficient iron.
3. Blood transfusion. It should be noted that blood transfusions are not always possible. Only in cases of severe anemia and cardiovascular instability should blood transfusions be used as an emergency response. This is just a temporary treatment. If blood is transfused too early, anemia will continue and it will not improve survival.