Can congenital infertility patients be cured? What is the treatment plan for congenital ovarian hypoplasia

Women with congenital diseases may not be able to resume normal fertility after treatment, but there are still ways to improve by adhering to certain measures. How to improve the ovaries?

Here are some tips for hormone therapy:

Firstly, patients with this disease cannot establish reproductive function. For the development and maintenance of the Secondary sex characteristic, estrogen replacement therapy can be used for a long time to prevent osteoporosis. However, long-term use of any type of estrogen carries the risk of inducing endometrial cancer.

Secondly, it advocates artificial cycle therapy with estrogen and Progestogen to induce periodic uterine bleeding. On the one hand, it is a psychological comfort for patients; On the other hand, regular peeling of the endometrium can prevent the occurrence of endometrial cancer.

Third, for people with short stature, Nandrolone phenylpropionate treatment has a good effect. But those with healed epiphyses have poor therapeutic effects. For chimeras containing Y chromosome, bilateral gonads should be removed to prevent malignant transformation.

Fourthly, estrogen alone can easily cause early healing of growth plates, limit bone growth, and inhibit growth potential. The application time of estrogen is crucial, usually not used before the age of 12, and it is best to use it after the age of 15.

In clinical practice, the treatment plan for congenital ovarian hypoplasia is as follows:

Experts say that improving the final height and sexual development in adulthood ensures the psychological health of children. Strive for early diagnosis, early use of genetic heavy foot human growth hormone, and subcutaneous injection of 0.15U/kg every night can significantly increase the height of the child. If their bone age lags significantly, they can be combined with the use of stanozolol 25-50 times a day μ Oral administration of g/kg has a better effect.

At the same time, thyroid function and bone age development should be regularly tested. When bone age reaches 12 or above, oral low-dose estrogen therapy can be started to promote breast and external genital development. Ethinylestradiol (10-20 μ G/d) or diethylstilbestrol (0.1-0.5mg/d) or progesterone, starting from 310 mg/day μ Starting from g, gradually increase the dosage based on clinical effects.

These are all precautions that women with congenital ovarian dysplasia should pay attention to. Of course, some patients should fully understand the treatment methods for congenital ovarian dysplasia, which is also recommended for women to pay attention to. Afterwards, we also need to take note of the precautions and be fully prepared to alleviate ovarian diseases!