Post Date November, 16 2024
AIDS, also known as acquired immunodeficiency syndrome (AIDS), is an infectious disease caused by human immunodeficiency virus (HIV) infection, which is mainly transmitted through sexual behavior, blood contact or mother to child contact transmission. After HIV infection, the immune function of the human body is suppressed, which can easily cause viral infection and tumors. After the human body is infected with HIV, it can cause damage to T lymphocytes, leading to persistent immune deficiency, opportunistic infections in multiple organs, rare malignant tumors, and ultimately death.
The lipoproteins of AIDS virus (HIV) in vitro are embedded into gp120 and gp41 glycoproteins. gp120 and CD4 glycoprotein on the surface of lymphocytes have affinity, and gp41, which can specifically bind to gp120, mediates the fusion of virus membrane and host cell membrane fusion. Therefore, HIV can selectively invade CD4+lymphocytes after reaching the bloodstream through areas of skin mucosal damage and other methods such as blood.
After HIV invades CD4+lymphocytes, under the action of viral reverse transcriptase, DNA is synthesized and integrated into the host cell's chromosomes. The integrated viral DNA can replicate within the cell, forming a complete viral body that is released outside the cell, causing cell death and infecting new cells
In the early stages of the epidemic, a large number of HIV replicates, causing viremia, and the expression of coat antigen p24, with clinical manifestations of acute HIV infection. A large amount of replication within HIV cells leads to damage and death of CD4+lymphocytes, and a significant decrease in CD4+T cells. However, under the immune function of the body, CD8+CTL is activated, killing HIV infected cells and producing anti HIV antibodies. Viremia is quickly cleared, and the CD4+lymphocyte count is restored.
Can kissing infect AIDS?
Can saliva infect AIDS? Generally speaking, kissing does not infect AIDS. HIV exists in the blood, semen, vaginal secretions, tears, urine, milk, and cerebrospinal fluid of infected people. The content of HIV in saliva is very small, and it will not infect human viruses. Under normal circumstances (no massive bleeding in the mouth), only HIV virus is contained in saliva. In order to achieve the effect of AIDS infection, it is necessary to put 2 gallons (7.5 liters) of saliva into the other party's body. In addition, so far, the scientific community has not found any cases of kissing infection.
AIDS treatment includes
1. General supportive therapy: including physical and mental rest and nutritional supply.
2. Control of opportunistic infections and treatment of malignant tumors: most of the opportunistic infections have special drugs, which use various antibacterial, antimycotic and antigenic drugs to treat opportunistic infections of AIDS patients under the guidance of doctors. Malignant tumors are treated with radiation, chemotherapy, or surgery at the discretion of the doctor.
