Post Date November, 16 2024
Endometrial cancer is a serious and highly harmful disease. We must understand its causes and take reasonable precautions through daily habits and diet.
Causes of endometrial cancer
1. Obesity: Excessive fat can increase the storage of estrogen, and testosterone in plasma can become estrone. This increase in free active estrone may be a carcinogenic or pro oncogenic factor in endometrial cancer.
2. Diabetes: diabetes patients and those with abnormal glucose tolerance have an increased risk of endometrial cancer by 2. Eight times.
3. Hypertension: There are more cases of endometrial cancer with hypertension. Obesity, diabetes and hypertension coexist in patients with endometrial cancer, which is called "endometrial triad" or "endometrial cancer syndrome". The three may be related to a high-fat diet, which is directly related to endometrial cancer.
4. Menstrual disorders: Patients with endometrial cancer have menstrual disorders and high menstrual volume, which are three times higher than normal women.
5. Early menarche and late amenorrhea: The incidence of endometrial cancer is 60% higher in those who have menarche before the age of 12 compared to those who have menarche after the age of 12. The most advanced age of endometrial cancer is 6 years later than that of normal women.
6. Pregnancy and childbirth frequency: Endometrial cancer occurs more frequently in cases of postpartum, postpartum, and infertility.
7. Polycystic ovary syndrome: Without ovulation, the endometrium undergoes proliferation changes due to insufficient regulation of pregnancy hormones and periodic endometrial dissection under high and sustained levels of estrogen.
8. Ovarian tumors: Granulocytic carcinoma, follicular thecoma, etc. that secrete high levels of estrogen, with irregular menstruation, bleeding after amenorrhea, endometrial hyperplasia, and endometrial cancer.
9. Atypical hyperplasia of the endometrium: stage of endometrial cancer development or absence of this stage. Severe atypical hyperplasia can be considered as endometrial carcinoma in situ.
10. Exogenous estrogen: Women who take estrogen have a high risk of developing endometrial cancer, which is related to the dosage, duration of use, whether to use progesterone together, whether to stop taking it in the middle, and patient characteristics. The risk decreased in gray after discontinuation, but the risk persisted for several years. At present, there is sufficient evidence of a causal relationship between estrogen and endometrial cancer.
Prevention of endometrial cancer
1. Carry out cancer prevention publicity and general survey, strengthen health and medical knowledge, educate women with abnormal menopausal bleeding, vaginal discharge, obesity, hypertension or diabetes, and increase vigilance, timely medical treatment and early diagnosis.
