Will marriage between close relatives lead to sexual deformities? Don't do things like preventing and treating sexual deformities

Sexual malformation, as the name suggests, refers to the blurry surface of the external genitalia, sometimes even unable to distinguish gender based on the shape of the external genitalia. Some boys have short penises, hypospadias, underdeveloped scrotum, and no testicles (cryptorchidism) in the scrotum after birth. Some severe patients may not even develop penises, manifested as female genitalia.

Some patients have urethral openings, which are located at the bottom of the penis rather than the top, making it difficult for them to urinate while standing and squatting. Their cryptorchidism, due to its inability to produce a large amount of androgens and sperm, may have a significant impact on the patient's future male development and reproductive function. A short penis may bring difficulties to future sexual life. The causes of these diseases may be related to the lack of genes for SRY androgen synthesis disorders, underdeveloped testicles, or inadequate biological effects of androgens.

What are the causes of hermaphroditism?

1. The cause of true hermaphroditism may be the mosaicism of monozygote chromosomes, which is caused by meiosis or mitotic errors; Non monozygotic chromosome mosaicism is usually the result of fusion or double fertilization of two zygote; Y chromosome is easily located on X chromosome.

Autosomal mutated genes. Autosomal recessive or dominant inheritance is the hereditary mode of familial patients.

2. The cause of pseudohermaphroditism may be that the female pseudohermaphroditism is caused by the fetus being exposed to an environment with excessive androgens. The specific reasons are three: congenital adrenal hyperplasia, lack of corticosteroid synthesis of 21 hydroxylase or 11 hydroxylase, and the mother suffering from male tumors during masculinization pregnancy., Such as ovarian cysts, luteal tumors, or ovarian male cell tumors that secrete excessive androgens, or benign tumors of the adrenal gland. The mother is masculinization during pregnancy., Feminized external genital morphology also occurs in the fetus. During pregnancy, the use of androgen drugs by mothers can also make female fetuses masculinization.

The main causes of male pseudohermaphroditism are dysfunction of testosterone synthesis and deficiency of anti mesonephric hormone reductase.

What should I do after sexual malformation?

Timely go to the hospital for further examination and clear diagnosis; Generally speaking, chromosome testing should determine gender before the age of 2. Because after the age of 2, children have a solid understanding of their gender, and if they forcibly change their gender in the future, it may lead to future sexual psychological abnormalities. Genuine hermaphroditism should be based on the etiology, especially the shape and psychological gender of the external genitalia, establish an appropriate gender, retain appropriate gonadal tissue, and enable children to develop to a more functional side. Male pseudohermaphroditism, if it is estimated that male sexual function cannot be achieved after surgery, should develop towards females; If feminization is insufficient;, Estrogen can be administered. Female pseudohermaphroditism usually leads to female development and the possibility of future fertility.