Post Date December, 02 2023
Prostate disease is a common male disease that has been troubling men's health and life. Men should not believe in some advertisements and expensive drugs to prevent prostate diseases. Scientific prevention is the most correct thing, and we must all believe in science. Let's learn about three ways to prevent prostate cancer.
Prostate disease is not terrible, men should not panic because of prostate disease. Prostate disease can be scientifically prevented, as long as we understand that prevention of prostate cancer can start from three points.
1. Census
Currently, the commonly accepted and effective method is to use digital rectal examination plus serum PSA concentration measurement.
"Using serum PSA levels to detect male citizens aged 40 to 45 years or older, and conducting follow-up testing once a year, this screening method is economical and effective. For example, if PSA exceeds 4.0 ng/ml, digital rectal examination or ultrasound examination should be performed, and if positive or suspicious, needle biopsy should be performed. This method can be very effective in detecting early localized prostate cancer.", A population-based survey in Sweden found that the time span from the increase in serum PSA concentration above 3 ng/ml to the clinical diagnosis of prostate cancer was 7 years. Therefore, conducting PSA surveys on the population can early diagnose prostate cancer and early treatment, because PSA blood concentration increases with age. A study by the Medical School of Gunma University in Japan found that the age range is 60 to 64 years, 65 to 69 years, and 70 to 74 years old, The upper limits of the age corrected normal values for blood PSA in men aged 75 to 79 years and over 80 years should be 3.0, 3.5, 4.0, and 7.0 ng/ml, respectively. The sensitivity, specificity, and effective rate of these normal ranges are 92.4%, 91.2%, and 84.3%, respectively. In the Austrian study, the normal upper limits for serum PSA concentrations in men aged 45 to 49 years and 50 to 59 years were 2.5 ng/ml and 3.5 ng/ml, respectively, Many studies can use the percentage of free PSA to increase the sensitivity of PSA determination for patients with serum PSA 4.0 to 10 ng/ml. Generally speaking, the increase in free PSA is seen in benign prostatic hyperplasia, while the decrease in free PSA is seen in patients with prostate cancer. Therefore, if the percentage of free PSA is less than 25%, it is likely (less than 10% probability) that there is no prostate cancer, "If 10% of patients have a high probability (60% to 80% probability) of suffering from prostate cancer, it is very meaningful to have a prostate biopsy at this time.".
2. Avoiding risk factors
This is difficult to achieve because there are many clear risk factors, such as genetics and age, that cannot be avoided, but potential environmental risk factors such as high fat diet, cadmium, herbicides, and other undetermined factors can be avoided. Currently, about 60% of the factors that cause prostate cancer are known to come from the living environment. Research from Sweden shows that occupational factors are related to prostate cancer, and the occupation with statistically significant risk is agriculture, In the related industrial soap making, perfume and leather industries, farmers, tanning workers and management staff in these industries all have a significant increase in incidence rate. In addition, people exposed to chemicals, herbicides and fertilizers all increase the risk of prostate cancer. According to New Zealand reports, fish oil containing antioxidants in food can protect and reduce the risk of prostate cancer. Taiwan reports that magnesium content in drinking water can prevent prostate cancer, In addition, adhering to a low fat diet, eating more soy foods rich in plant protein, drinking Chinese green tea for a long time, and appropriately increasing the content of trace elements selenium and vitamin E in the diet can also prevent the occurrence of prostate cancer.
3. Chemical prevention
Chemoprevention can be divided into the following main categories based on the intervention methods of drugs, such as tumor genesis inhibitors, anti tumor growth drugs, and tumor progression inhibitors. Because the occurrence and development of prostate cancer is a long-term process, we can use drugs to prevent or suppress the occurrence and development of prostate cancer, For example, finasteride can inhibit the transformation of testosterone into dihydrotestosterone, an active substance that has a strong effect on the prostate, so it may inhibit the growth promoting effect of testosterone on prostate cancer cells. Currently, this effect is still under clinical research and observation, and remains to be confirmed. Other drugs such as retinol have the effects of promoting cell differentiation and anti tumor progression, and are also under clinical research, potentially becoming potential chemopreventive drugs.
The above introduction is aimed at understanding prostate diseases. Men want scientific prevention to be simple. Screening, avoiding risk factors, and chemical prevention of prostate cancer can start from three points.
