Post Date December, 03 2023
There are five common types of drugs that affect male reproductive function:
1、 Hormonal drugs.
The application of drugs such as estrogen, progesterone, and testosterone propionate can inhibit the secretion of gonadotropins in the pituitary gland, thereby inhibiting the spermatogenic function of the testes.
2、 Drugs that directly inhibit sperm production.
Dichlorodiacyldiamines are insecticides, but they also have an inhibitory effect on spermatogenesis; Other drugs, such as dinitropyrroles, nitrofurans, anticancer alkylating agents, and recently studied gossypol extracted from cottonseed, have a strong inhibitory effect on testicular spermatogenesis.
3、 Drugs that affect sperm maturation.
The application of anti androgen compounds such as methyl chloroprogesterone acetate and chloroglycerol drugs may not have a significant impact on the function of testicular sperm, but these drugs have a direct effect on the sperm produced by the testes, causing them to fail to mature and lose their fertilization ability.
4、 Drugs that affect ejaculation.
Drugs such as acetaminophen and methylthiazide, which are used to treat hypertension, can reduce or even prevent ejaculation in patients. Some drugs can inhibit ejaculatory reflex and delay ejaculation, such as tranquilizers, chlorpromazine, etc.
5、 Many topical drugs, such as surfactants, organometallic compounds (such as phenylmercury acetate), and weak acids, have a direct effect on killing sperm.
If such topical drugs are frequently used to treat female reproductive tract diseases, such as vaginal plugs, it will inevitably affect fertility.
