Post Date December, 02 2023
The causes of benign prostatic hyperplasia have not been fully elucidated so far. There have been theories of race, body type, social factors, metabolic and nutritional factors, neobiology, arteriosclerosis, inflammation, and endocrinology, but most of them have not been universally recognized.
So, what is the etiology and pathogenesis of anterior lacrimal gland hyperplasia? Let's give you a brief introduction.
The etiology and pathogenesis of benign prostatic hyperplasia
In recent years, explanations for the etiology of this disease have mostly focused on sexual hormone imbalance. Research has shown that the testicles of normal people mainly produce androgens, but also produce trace amounts of estrogen. In addition, the adrenal reticular zone also secretes a small amount of estrogen.
Experts say that there is a significant balance between male and estrogen. The balance and coordination of androgens and estrogen in the body is a basic condition for the normal development of the prostate. In old age, if the balance between male and female hormones is unbalanced, it can cause prostate hyperplasia.
① In pre puberty, the prostate gland is still undeveloped, small in size, and without normal function. With age, blood testosterone levels increase, and the prostate gland rapidly increases to reach its highest functional state.
② In adolescence, when the testicles are removed or stunted, the prostate cannot develop normally.
③ Prostatic hyperplasia never occurs in young people or in people who have had their testicles removed or have been castrated during their youth.
④ The content of dihydrotestosterone in benign prostatic hyperplasia tissue is 3-4 times higher than that in peripheral normal prostate tissue, and the content of dihydrotestosterone in the nucleus is 3-4 times higher than that in the cytoplasm.
⑤ In mammals, only humans and dogs have prostate hyperplasia, and the amount of dihydrotestosterone does not decrease after aging. Adequate administration of dihydrotestosterone can cause prostate hyperplasia in ovariectomized domestic dogs, and only exogenous male hormones that make the amount of dihydrotestosterone in the prostate tissue of domestic dogs higher than normal can induce prostate hyperplasia.
