Post Date December, 03 2023
Diuretic
Spironolactone has an anti androgenic effect. If used for a long time, it can cause sexual dysfunction or impotence in men, irregular menstruation and amenorrhea in women, and even stop ovulation. Furosemide and diuretic acid can induce hypokalemia, leading to impotence, but potassium supplementation can improve the condition.
Anticancer drugs
Bactrian can cause testicular atrophy in men and amenorrhea in women. Cyclophosphamide can cause sperm and semen deficiency in men, amenorrhea or irregular menstruation in women.
Antihypertensive drugs
These drugs are most closely related to sexual dysfunction such as decreased libido, loss of orgasm, and impotence. If the daily dosage of guanethidine is above 25 mg, most male patients will experience adverse reactions such as impotence, delayed ejaculation, or inability to ejaculate, while female patients will experience insufficient vaginal lubrication and decreased libido. "Although the daily dose of methyldopa is less than 1 gram, it can still cause decreased libido or impotence in men, amenorrhea, galactorrhea, and decreased sexual excitement in women.". Reserpine can also reduce libido in most male patients, cause impotence, and even induce a history of depression. Patients with a history of depression should not choose reserpine. In addition, clonidine, hydralazine, meglumine, and prazosin can also cause sexual dysfunction.
Anticardiac drugs
Digitalis, digoxin, and cardiotonic drugs used in congestive heart failure can cause sexual dysfunction or impotence in men.
