Post Date December, 02 2023
Pathology:
The etiology of non eosinophilic granulomatous prostatitis may be a foreign body tissue reaction to exosmotic prostatic fluid. This disease is characterized by rapid progress of these symptoms, which soon develop into urinary retention. Non eosinophilic granulomatous prostatitis often occurs in the elderly and is caused by the reaction and proliferation of the prostate to foreign bodies such as bacterial products that stagnate in the tissue.
Clinical manifestations:
The clinical symptoms of non eosinophilic granulomatous prostatitis include symptoms of urinary tract infection, bladder outlet obstruction, such as fever, chills, frequent urination, urgency, pain in urination, occasional hematuria, perineal pain, and discomfort, poor urination, thin urinary lines, weakness in urine, and post urination drippings.
Diagnosis and treatment:
Yellow, small, hard nodules can be seen on the section of the prostate. Microscopically, this is a non caseous granuloma with central liquefaction and necrosis. There are major histiocytes in the lumen near the gland, surrounded by lymphocytes, plasma cells, and eosinophils. Epithelioid cells are often confused with cancer, in addition to Langerhans cells and foreign body giant cells. Sperm can be seen in phagocytes, and fat and foam inclusions can be seen in granuloma.
Digital rectal examination can touch prostate nodules, which develop rapidly, are large, elastic, irregular, and inconsistent in soft and hard. Non eosinophilic granulomatous prostatitis must be differentiated from prostate cancer. Routine urine examination can exclude white blood cells, and white blood cells can increase. The diagnosis depends on prostate biopsy.
Corticosteroids and antibiotics can be used for treatment. Patients with obvious obstructive symptoms can undergo surgical resection of the prostate, with good results.
