Post Date December, 03 2023
In the past, it was called "the disease of wealth". However, with the improvement of living standards and the change of diet, the incidence rate of gout is getting higher and higher.
As a disease mainly caused by uric acid accumulation, long-term high uric acid can lead to the deposition of gout stones in the kidneys, causing necrosis of kidney tissue, and in severe cases, can lead to uremia.
According to epidemiological studies, 20% to 40% of gout patients will develop gouty nephropathy, and once they do, they need to be prepared for a prolonged battle against renal failure.
There are also many kidney friends who suffer from gouty nephropathy on the Love Kidney Network platform. They not only have to endure the various hardships brought by chronic kidney disease, but also the discomfort brought by gout to the body.
Many patients with gouty nephropathy know that uric acid is the final product of purine in the body, and it is important to limit the intake of high purine foods. However, few kidney friends know that excessive intake of fructose is also a major risk for gouty nephropathy patients.
Fructose
It is a monosaccharide, the sweetest of all monosaccharides, and also sweeter than the most commonly used sucrose.
Since the United States broke through the bottleneck in producing fructose in the 1970s, fructose has been widely used in the food industry and is widely added to sweet drinks, pastries, and candies. As a result, human consumption of fructose has significantly increased in the past few decades.
Through epidemiological investigation, some scholars found that the incidence rate of Shepard syndrome in developed countries represented by the United States increased significantly in the past decades, which was parallel to the excessive intake of fructose.
Therefore, the adverse effects of fructose on the human body have attracted the attention of many scholars, and a large number of studies have shown that fructose has the potential to induce elevated levels of uric acid, blood pressure, and blood lipids in the human body.
Kidney friends with high uric acid are most concerned about the relationship between fructose and uric acid, so why can fructose induce an increase in human uric acid levels?
This is related to the metabolic pathway of fructose. As a monosaccharide, fructose can be easily absorbed into human cells by the role of small intestinal mucosa.
Unlike glucose, fructose metabolism does not exhibit inhibitory effects, resulting in rapid depletion of ATP (the most important energy source in the human body).
After ATP depletion, it can activate the activity of purine metabolism enzymes and produce excessive AMP (also an energy supply substance in the human body), which ultimately decomposes into uric acid.
01
Sweet drinks, pastries, candies
As beneficiaries of fructose industrialization, sweet drinks (including sugary drinks such as juice and cola), candies, pastries, and other processed foods are the most abundant sources of fructose. Eating seafood with sweet drinks is no less harmful to kidney patients with gout than drinking beer.
Not only that, most sweet drinks also add phosphoric acid as a preservative. If kidney friends with gout experience symptoms of oliguria, anuria, edema, or high blood phosphorus, it is easy to become dangerous after drinking.
02
Fruits and honey
Fruits and honey contain a large amount of fructose, and kidney friends with gout should not consume excessive amounts. But kidney friends should not give up eating because of choking. Fruits can supplement the body's vitamins, minerals, and dietary fiber.
According to the "Dietary Guidelines for Chinese Residents (2016)", the recommended intake of fruits should be controlled at 200g (4 liang) per day.
Although honey has a high fructose content, it has various health benefits and can be consumed in moderation every day.
In addition to supplementing energy, the acetylcholine contained in honey can also stimulate gastrointestinal peristalsis, which has a certain effect on preventing constipation in kidney friends.
As mentioned earlier, the harm of fructose to the human body began to emerge in large quantities when fructose was added to processed foods on a large scale. So consuming natural foods containing fructose such as fruits and honey in moderation will not cause harm to the human body, and there are also certain benefits to the human body.
