How do I need to check for stage three syphilis? What are the methods for checking for stage three syphilis

How do I need to check for stage three syphilis? Syphilis is a chronic sexually transmitted disease that is mainly transmitted through sexual intercourse and can cause damage to multiple organs throughout the body. Syphilis can be divided into three stages according to its severity. If syphilis develops into three stages in women, it may be transmitted to the next generation through the placenta. Causing congenital syphilis in newborns is extremely harmful. So, what kind of examination should be done? Has the diagnosis of syphilis progressed to stage three?

Phase III syphilis generally requires a comprehensive physical examination, including the entire body's skin, mucosa, bones, oral cavity, external genitalia, anus, surface lymph nodes, and other parts. Elderly individuals with the disease should undergo cardiovascular and neurological examinations. Other specific inspections are as follows.

Method for checking for stage three syphilis:

1. Treponema pallidum test.

2. Dark field microscopy examination: At the site of skin injury, use glass scraping to remove tissue exudate and lymph node puncture fluid, and see active Treponema pallidum.

3. Immunofluorescence staining: Green Treponema pallidum can be seen under a fluorescence microscope.

4. Syphilis serum test.

5. According to the different antigens used, syphilis serum tests are divided into the following two categories:

（1） Non Treponema pallidum antigen serum test, using cardiolipin as the antigen, measures anticardiolipin antibodies in serum, also known as reactive elements.

(1) Rapid plasma reagin test: It is an improvement of VDRL antigen, with sensitivity and specificity similar to VDRL, and the advantage is that the results can be read by the naked eye;

(2) The unheated serum reagin slide test is also an improvement of VDRL antigen, with sensitivity and specificity similar to VDRL.

（2） Treponema pallidum antigen serum test

(1) Fluorescent Treponema pallidum antibody absorption test: This method is a more sensitive and specific spirochete test;

(2) Phase III Treponema pallidum hemagglutination test: Both sensitivity and specificity are high, and the operation is simple, but it is not as sensitive to Phase I syphilis as the FTA-ABS test.

Do you understand how to check for stage three syphilis? If you find yourself feeling unwell, you should go to the hospital for a detailed examination in a timely manner. Once diagnosed, you should receive timely treatment for syphilis.