The World Health Organization's multiple research centers evaluated the factors related to abnormal semen quality through statistical processing and analysis of data from 7273 infertile couples. Here we introduce these situations to readers in order to give them a global understanding of the causes of infertility.
1、 Sexually transmitted diseases
In the entire population, the incidence of azoospermia is similar between individuals with and without sexually transmitted diseases, but the former has a significantly higher incidence of abnormal semen analysis. Sexually transmitted diseases do not seem to affect sperm density, indicating that they do not cause narrowing or blockage of the vas deferens. Individuals with sexually transmitted diseases generally exhibit a decrease in sperm motility, which is related to dysfunction of the accessory glands, especially epididymitis.
2、 Parotitis
The occurrence of mumps before and after puberty does not increase the incidence of azoospermia, but is associated with a higher likelihood of abnormal semen. The sperm density of individuals with onset after puberty is significantly lower than that of those without onset or those with onset before puberty.
Only 4.4% of patients with mumps have orchitis. Prepubertal patients rarely develop orchitis, but it can occur after puberty. Testitis significantly affects sperm quality and increases the incidence rate of azoospermia, especially bilateral orchitis. Whether it is unilateral or bilateral orchitis, there is an increase in cases of abnormal semen analysis. In short, mumps, especially when combined with orchitis, can have adverse effects on fertility.
3、 Bronchitis
Bronchitis is often a clinical manifestation of ciliary dysfunction that extends throughout the body. The incidence of azoospermia is significantly higher in these patients. All of these patients have normal testicular volume, indicating that azoospermia is caused by blocked vas deferens. The abnormal rate of semen analysis in patients with bronchitis increases, and the average sperm density and proportion of sperm moving forward are lower.
4、 Diabetes
Diabetes is related to ejaculatory dysfunction and does not cause azoospermia or abnormal sperm quality. Therefore, the impact of diabetes on fertility is caused by sexual dysfunction.
5、 Recent history of high fever
It is already known that 33 ° C is the most suitable temperature for the testes, and when the temperature of the testes increases, it can damage their spermatogenic function. Fever exceeding 38 ° C can cause a temporary decrease in semen quality and fertility.
Patients with a history of high fever within 6 months showed a significant increase in abnormal semen analysis, especially a significant decrease in sperm density compared to those without a recent history of fever. However, there was no significant difference in the incidence of azoospermia between the two groups of patients.