Post Date November, 17 2024
The emergence of endometriosis has caused great distress to many women, and it is also a highly harmful gynecological disease. After getting sick, we must actively treat and regulate it.
Can endometriosis lead to pregnancy
Infertility experts point out that the infertility rate in normal women is about 15%, while patients with endometriosis can reach up to 40%. Endometriosis is a gynecological disease caused by the growth of the endometrium in any area outside the uterine cavity. Ovaries, uterosacral ligaments, serous layer of the lower uterine posterior wall, uterorectal traps, sigmoid colon pelvic peritoneum, etc. can also occur in the myometrium.
The causes of infertility caused by endometriosis
1. Endotopia will cause extensive adhesion of pelvic tissues, forming a lump, affecting the oviduct's function of taking eggs, which is not conducive to the transport of zygote. The invasion of the focus into the ovary will also cause ovulation dysfunction
2. Endometriosis can also cause ovarian dysfunction, such as anovulation, luteal insufficiency, decreased egg quality, decreased fertilization rate, and low success rate of implantation
3. Patients with endometriosis also have poor pelvic environmental conditions, with an increase in the number and activity of giant cells in the pelvic fluid, which can easily affect women's physical activity and lead to pregnancy
Treatment of endometriosis
1. Drug therapy: including symptomatic treatment for pain suppression, inhibition of estrogen synthesis, inhibition of ectopic endometrial atrophy, inhibition of hypothalamic pituitary ovarian axis stimulation, and sexual hormone therapy for the purpose of bleeding cycles. It is suitable for patients with chronic pelvic pain, obvious menstrual dysmenorrhea symptoms, fertility requirements, and no ovarian cysts.
(1) Oral contraceptive pills: reduce pituitary gonadal hormone levels, directly affect the endometrium and ectopic endometrium, resulting in endometrial atrophy and decreased menstrual flow. At present, low-dose and high-efficiency progesterone ethinylestradiol composite preparations are commonly used in clinical practice, with a daily dosage of 1 tablet and continuous use for 6-9 months. It is suitable for patients with mild endometriosis.
(2) Progesterone: Using artificially synthesized and highly efficient progesterone alone, it inhibits the secretion of pituitary gonadotropins, resulting in an acyclic low estrogen state. It works together with endogenous estrogen to cause high progesterone induced amenorrhea and endometrial decidualization, forming pseudopregnancy. The dosage used is 3-4 times the contraceptive dose, used continuously for 6 months..
