Post Date November, 16 2024
Human immunodeficiency virus (HIV) is a virus with systemic defects. In 1983, HIV was first discovered in the United States. It is a lentivirus that infects cells of the human immune system and is a type of retrovirus.
Why is AIDS so difficult to cure
HIV destroys human t lymphocytes, cuts off cellular and humoral immune processes, paralyzes the immune system, spreads various diseases in the human body, and finally causes AIDS. Due to the rapid mutation of HIV, specific vaccines are difficult to produce, and there are currently no effective treatment methods, posing a serious threat to human health.
So far, only one Berlin patient Timothy Brown is believed to have completely cured HIV worldwide. In 2007, after receiving leukemia treatment at a German hospital, Brown's HIV virus completely disappeared from his body. When treating leukemia, Brown first receives radiation therapy, which is used to kill cancer cells and produce stem cells from bones. Then, through bone marrow transplantation surgery, he is implanted into the bone marrow of healthy individuals to produce new blood cells. After receiving treatment, Teacher Brown's leukemia has improved, and the level of HIV virus in his body has also sharply decreased, and the instrument cannot detect it. I am glad that Brown has not yet detected the HIV virus, and what is even more surprising is that ordinary HIV patients have not taken the anti retroviral enzyme virus drugs that must be taken. However, when scientists later conducted this therapy in monkeys and HIV patients with lymphoma, the result was that HIV could not be cured. Based on this, scientists believe that individuals who donate bone marrow to Brown play an indispensable and important role. The reason is that the donor's gene CCR5 has undergone a rare mutation.
This is just a small interlude, after all, there is only one example and cannot be copied. The persistence and resilience of HIV infection have been well documented. Since the 1980s, significant medical advancements have transformed HIV/AIDS from a terminal illness to a controllable disease. Currently, antiretroviral drugs are commonly used in combination, including entry inhibitors, which function as nucleoside reverse recording enzyme inhibitors that interfere with HIV binding to host cells. Their function is to inhibit the synthesis of HIV into host cell DNA as a comprehensive enzyme inhibitor, and their function is to block important HIV virus enzymes, namely comprehensive enzymes. However, vaccines, drugs, and therapies have not yet permanently cured HIV infected individuals.
